PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8043506-5	1994	Prazosin significantly reduced the total number of LHRH mRNA expressing cells, and increased the total number of POMC mRNA expressing cells and the concentration of POMC mRNA per cell.	Prazosin	0-8	gonadotropin releasing hormone 1	Rattus norvegicus	51-55	
15500541-4	2004	Norepinephrine significantly stimulated GnRH release from proestrous basal hypothalamus explants, and coadministration of the alpha(1)-adrenergic antagonist prazosin blocked this effect.	Prazosin	157-165	gonadotropin releasing hormone 1	Rattus norvegicus	40-44	
11999719-5	2002	Treatment with prazosin and yohimbine prevented the pheromonal restoration of cyclic activity, the drop of LHRH and the rise of plasma concentration of the studied hormones induced by male urine, while saline or propranolol did not.	Prazosin	15-23	gonadotropin releasing hormone 1	Rattus norvegicus	107-111	
26556532-5	2016	Prazosin, administered 5 and 3 hours prior to the predicted time of the LH surge truncated the LH surge and abolished the rise in GnRH and kisspeptin in the median eminence.	Prazosin	0-8	gonadotropin releasing hormone 1	Rattus norvegicus	130-134	
8381912-11	1993	When the number of grains in LHRH-expressing neurons were totalled, EB increased (P < 0.05) LHRH gene expression by 53%, and local administration of prazosin completely blocked (P < 0.01) this increase.	Prazosin	152-160	gonadotropin releasing hormone 1	Rattus norvegicus	29-33	
1363791-4	1992	Attempts to block the muscarinic-antagonist-induced stimulation of GnRH release with a variety of drugs were successful only in the presence of prazosin, an antagonist to alpha 1-adrenergic receptors.	Prazosin	144-152	gonadotropin releasing hormone 1	Rattus norvegicus	67-71	
6096749-3	1984	Adrenoceptor antagonists (10(-6) M) were also tested: prazosin (alpha 1-antagonist) and phentolamine (alpha 1/alpha 2-antagonist) almost completely suppressed the enhanced release of LH-RH induced by NA.	Prazosin	54-62	gonadotropin releasing hormone 1	Rattus norvegicus	183-188	
1699747-9	1990	The addition to the medium of the alpha-adrenergic blocker phentolamine or prazosin impaired the ability of rGAL to release both LHRH and PGE2.	Prazosin	75-83	gonadotropin releasing hormone 1	Rattus norvegicus	129-133	
21554614-8	1992	Compared to the controls, prazosin caused a 32% decrease (P<0.05) in the number of cells expressing the LHRH gene.	Prazosin	26-34	gonadotropin releasing hormone 1	Rattus norvegicus	107-111	
3075044-4	1988	The systemic administration of either prazosin, an alpha-adrenergic antagonist (0.2 or 1 mg/kg), or propranolol, a beta-adrenergic antagonist (20 mg/kg), totally suppressed LHRH-induced lordosis in sexually inexperienced Ss (mean LQs = 8 +/- 11; 5 +/- 10; 18 +/- 31, respectively).	Prazosin	38-46	gonadotropin releasing hormone 1	Rattus norvegicus	173-177