PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9335414-7	1997	Captopril, prazosin, and verapamil reduced fasting insulin levels, whereas atenolol and hydrochlorothiazide did not.	Prazosin	11-19	insulin	Homo sapiens	51-58	
12555491-3	2000	OBJECTIVE: The aim of this study was to evaluate the effectiveness and the safety of prazosin osmotic tablet treatment in non-insulin-dependent diabetic patients with mild to moderate arterial hypertension.	Prazosin	85-93	insulin	Homo sapiens	126-133	
9335414-11	1997	The BP reduction resulting from the peripheral vasodilation may explain the insulin-reducing action of captopril, verapamil, and prazosin.	Prazosin	129-137	insulin	Homo sapiens	76-83	
8628189-0	1995	[The effect of cilazapril and prazosin on insulin sensitivity in patients with essential hypertension].	Prazosin	30-38	insulin	Homo sapiens	42-49	
8628189-2	1995	The objective of this study was to examine short-term effects of cilazapril and prazosin therapy on insulin sensitivity assessed by a 15" test of insulin tolerance of obese hypertensive persons.	Prazosin	80-88	insulin	Homo sapiens	100-107	
2643861-5	1989	However, the plasma insulin response from 8 A.M. to 4 P.M. decreased significantly (p less than 0.001) following prazosin treatment.	Prazosin	113-121	insulin	Homo sapiens	20-27	
8479941-3	1993	12 month therapy with prazosin enhanced insulin and suppressed gastrin secretion stimulated by test meal in comparison to the pretreatment values.	Prazosin	22-30	insulin	Homo sapiens	40-47	
8479941-5	1993	Our results suggest, that long term prazosin treatment markedly influenced insulin and gastrin secretion in patients with EH.	Prazosin	36-44	insulin	Homo sapiens	75-82	
8479941-0	1993	[Effect of long term prazosin treatment on secretion of insulin, glucagon, gastrin, and pancreatic polypeptide in patients with essential hypertension].	Prazosin	21-29	insulin	Homo sapiens	56-63	
1748056-3	1991	alpha-Adrenergic blockade with prazosin and angiotensin-converting enzyme (ACE) inhibition with captopril enhance insulin sensitivity.	Prazosin	31-39	insulin	Homo sapiens	114-121	
2643861-9	1989	In this study, treatment of mild hypertension with prazosin led to lower blood pressures and changes in insulin and lipoprotein metabolism that are important in this patient population.	Prazosin	51-59	insulin	Homo sapiens	104-111	
3511690-6	1986	However, prazosin was associated with an increase in the fasting blood glucose level and a decrease in the peak insulin value after glucose injection, both of which were dose-related effects.	Prazosin	9-17	insulin	Homo sapiens	112-119	
3065104-0	1988	Application of prazosin is associated with an increase of insulin sensitivity in obese patients with hypertension.	Prazosin	15-23	insulin	Homo sapiens	58-65	
3511690-7	1986	The data indicate that the glucose turnover was at least as good after a switch from diuretic to prazosin treatment as before at lower insulin values.	Prazosin	97-105	insulin	Homo sapiens	135-142	
3007797-0	1985	Vasodepressor effects of prazosin during insulin-induced hypoglycemia in hypertensive patients.	Prazosin	25-33	insulin	Homo sapiens	41-48	
6130677-3	1982	Ninety minutes after a single oral dose of 2 mg prazosin we observed a significant (p less than 0.05) fall in K-value (mean decrease from 1.7 to 1.0), which was accompanied by a blunting of the early insulin response.	Prazosin	48-56	insulin	Homo sapiens	200-207	
6130677-5	1982	It is postulated that the effect of prazosin is mediated by an increase in circulating catecholamines acting on the pancreatic beta-cell alpha 2-adrenoceptors, which are responsible for the well-known inhibitory action of alpha-adrenergic agents upon the release of insulin.	Prazosin	36-44	insulin	Homo sapiens	266-273	
7027200-0	1981	[Blood insulin and glucose in essential hypertension treated with prazosin].	Prazosin	66-74	insulin	Homo sapiens	7-14