PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30287134-7 2018 : Because of the increasing exposure of children to prazosin, clinicians should be aware of the pharmacology behind alpha-1 antagonist overdose and consider treatment options, such as vasopressin, when hypotension is resistant to standard fluid and catecholamine therapy. Prazosin 52-60 arginine vasopressin Homo sapiens 184-195 3512121-7 1986 However, in patients with lower renin levels, prazosin decreased pulmonary capillary wedge pressure (24.8 to 21.8 mm Hg, p less than .05), decreased plasma arginine vasopressin (1.16 to 0.75 pg/ml, p less than .05), increased water excretion (62% to 85%, p less than .005), and decreased plasma epinephrine (81 to 46 pg/ml, p less than .05), while in patients with higher renin levels none of these beneficial effects were noted. Prazosin 46-54 arginine vasopressin Homo sapiens 165-176 27403159-5 2016 MDMA lowered serum sodium but did not increase ADH or copeptin, although the control prazosin did increase ADH. Prazosin 85-93 arginine vasopressin Homo sapiens 107-110