PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7957629-3 1994 Ex vivo, clozapine (inhibitory dose (ID)50 = 0.7 mg/kg s.c.) mimicked prazosin (0.5) in potently occupying central alpha 1-adrenoceptors whereas, as compared to 8-OH-DPAT (0.2), it failed to occupy 5-HT1A receptors (> 10.0). Prazosin 70-78 5-hydroxytryptamine receptor 1A Rattus norvegicus 198-204 7909554-4 1994 STFs elicited by the 5-HT1A agonist 8-OH-DPAT were potently blocked by the alpha 1-adrenoceptor antagonist prazosin, as well as by WB 4101 and 5-methylurapidil, antagonists with a preference for the alpha 1A-subtype of adrenoceptor. Prazosin 107-115 5-hydroxytryptamine receptor 1A Rattus norvegicus 21-27 7909555-11 1994 STFs elicited by (+)-flesinoxan and LY 165,163 in the presence of cirazoline or ST 587 were blocked not only by prazosin but also by (-)-alprenolol, BMY 7378 and S 15535, all of which are antagonists of postsynaptic 5-HT1A receptors. Prazosin 112-120 5-hydroxytryptamine receptor 1A Rattus norvegicus 216-222 7913223-4 1994 The anticonflict effects of pindolol and cyanopindolol were completely abolished by the 5-HT1A receptor and alpha 1-adrenoceptor antagonist 1-(2-methoxyphenyl)-4-[4-(2-phtalimmido)butyl]piperazine (NAN-190), but were not modified by the selective alpha 1(-)-adrenoceptor antagonist prazosin. Prazosin 282-290 5-hydroxytryptamine receptor 1A Rattus norvegicus 88-94 1335222-4 1992 5HT1A and alpha 1-adrenergic receptors were determined by using [3H]-8-hydroxy-2-(di-N-propylamino)tetralin and [3H]-prazosin as radioligand, respectively. Prazosin 112-125 5-hydroxytryptamine receptor 1A Rattus norvegicus 0-5 1360535-3 1992 The anticonflict effect of ipsapirone in PCA-pretreated rats was antagonized by the 5-HT1A receptor and alpha 1-adrenoceptor antagonist NAN-190 (1-(2-methoxyphenyl)-4-[4-(2-phthalimmido)]butylpiperazine hydrobromide; 0.5-1 mg kg-1), but not by the selective alpha 1-adrenoceptor blocker prazosin (0.5 mg kg-1). Prazosin 287-295 5-hydroxytryptamine receptor 1A Rattus norvegicus 84-90