PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17664022-12 2007 Prazosin (alpha1- and alpha2B-adrenoceptor antagonist, 0.07-0.28 micromol/kg, i.v.) Prazosin 0-8 adrenoceptor alpha 2B Rattus norvegicus 10-42 15087625-11 2004 Prazosin, the alpha 1-/alpha 2B-adrenoceptor antagonist, attenuated the analgesic effect of nitrous oxide and prevented dexmedetomidine-induced reversal of tolerance to nitrous oxide. Prazosin 0-8 adrenoceptor alpha 2B Rattus norvegicus 14-44 8097565-5 1993 The concentration response curve of methoxamine was shifted to the right by the alpha 1/alpha 2B-adrenoceptor antagonist prazosin (0.1 mumol/l) with a pKD of 7.41 and that of UK 14304 by prazosin (0.3 mumol/l) with a pKD of 6.24. Prazosin 121-129 adrenoceptor alpha 2B Rattus norvegicus 80-109 1719824-3 1991 alpha 2-Adrenoceptor ligands inhibited [3H]rauwolscine binding with a rank order of potency characteristic of interaction with the alpha 2B-adrenoceptor [inhibitory constant (Ki) values (in nM) rauwolscine (1.95) greater than ARC-239 (8.52) greater than prazosin (237) greater than oxymetazoline (30,000)]. Prazosin 254-262 adrenoceptor alpha 2B Rattus norvegicus 131-152