PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12648529-5	2003	In neonatal rat cardiomyocytes, norepinephrine-induced ERKs activation was inhibited by an alpha(1)-adrenoceptor blocker (prazosin), but not by an beta-adrenoceptor blocker (propranolol).	Prazosin	122-130	mitogen activated protein kinase 3	Rattus norvegicus	55-59	
12648529-6	2003	Overexpression of the G(h) protein stimulated norepinephrine-induced ERKs activation, which was inhibited by alpha-adrenoceptor blocker (prazosin).	Prazosin	137-145	mitogen activated protein kinase 3	Rattus norvegicus	69-73	
11273730-4	2001	Activated MEK1/2 signals remained detectable at 2 h, and activated ERK1/2 remained detectable at 48 h. The alpha1-AR selective inhibitor prazosin (100 nM) completely inhibited the NE/Pro-stimulated activation of Ras, MEK1/2 and ERK1/2.	Prazosin	137-145	mitogen activated protein kinase 3	Rattus norvegicus	67-73	
11273730-4	2001	Activated MEK1/2 signals remained detectable at 2 h, and activated ERK1/2 remained detectable at 48 h. The alpha1-AR selective inhibitor prazosin (100 nM) completely inhibited the NE/Pro-stimulated activation of Ras, MEK1/2 and ERK1/2.	Prazosin	137-145	mitogen activated protein kinase 3	Rattus norvegicus	228-234	
11108260-3	2000	Treatment with prazosin or propranolol significantly reduced the effect of NE on MAPK phosphorylation, suggesting the involvement of both alpha- and beta-adrenergic receptors.	Prazosin	15-23	mitogen activated protein kinase 3	Rattus norvegicus	81-85	
17936747-4	2008	ERK1/2 activation was blocked by either prazosin or HEAT, indicating alpha(1)-adrenoceptors stimulate ERK1/2 in native glands and SMG-C10 cells.	Prazosin	40-48	mitogen activated protein kinase 3	Rattus norvegicus	0-6