PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29889817-6	2019	PE inhibited LPS-induced caspase-3 activation in ARVMs, which was reversed by prazosin (a membrane permeable alpha1-AR antagonist), but not by CGP12177A (a membrane impermeable alpha1-AR antagonist).	Prazosin	78-86	caspase 3	Rattus norvegicus	25-34	
35426094-8	2022	Accordingly, prazosin pretreatment in IR model rats could significantly increase the antioxidant capacity and attenuate apoptotic pathways by increasing the bcl-2 levels and decreasing the expression of Bax and caspase 3 enzymes (P<0.05).	Prazosin	13-21	caspase 3	Rattus norvegicus	211-220	
21614555-7	2011	When the autophagy pathway was inhibited, prazosin still induced programmed cell death, at least in part through apoptotic caspase-3 cascade enhancement.	Prazosin	42-50	caspase 3	Rattus norvegicus	123-132