PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23649895-11 2013 NAG and its analogue and orphan drug N-carbamoyl-l-glutamate, protected human CPS1 against proteolytic and thermal inactivation in the presence of MgATP, raising hopes of treating CPS1D by chemical chaperoning with N-carbamoyl-l-glutamate. N-carbamylglutamate 215-238 N-acetyl-alpha-glucosaminidase Homo sapiens 0-3 29055942-2 2017 Oral administration of N-carbamoylglutamate (NCG), a synthetic analog of N-acetylglutamate (NAG), successfully decreases plasma ammonia levels in the affected children. N-carbamylglutamate 23-43 N-acetyl-alpha-glucosaminidase Homo sapiens 92-95 29055942-2 2017 Oral administration of N-carbamoylglutamate (NCG), a synthetic analog of N-acetylglutamate (NAG), successfully decreases plasma ammonia levels in the affected children. N-carbamylglutamate 45-48 N-acetyl-alpha-glucosaminidase Homo sapiens 92-95 26059772-6 2015 Patients with NAG affinity-decreasing mutations might benefit from NAG site saturation therapy with N-carbamyl-L-glutamate (a registered drug, the analog of NAG). N-carbamylglutamate 100-122 N-acetyl-alpha-glucosaminidase Homo sapiens 14-17 26059772-6 2015 Patients with NAG affinity-decreasing mutations might benefit from NAG site saturation therapy with N-carbamyl-L-glutamate (a registered drug, the analog of NAG). N-carbamylglutamate 100-122 N-acetyl-alpha-glucosaminidase Homo sapiens 67-70 26059772-6 2015 Patients with NAG affinity-decreasing mutations might benefit from NAG site saturation therapy with N-carbamyl-L-glutamate (a registered drug, the analog of NAG). N-carbamylglutamate 100-122 N-acetyl-alpha-glucosaminidase Homo sapiens 67-70 27570737-3 2016 Although NAGS deficiency is the rarest urea cycle disorder, it is the only one that can be specifically and effectively treated by a drug, N-carbamylglutamate, a stable structural analogous of NAG that activates CPS1. N-carbamylglutamate 139-158 N-acetyl-alpha-glucosaminidase Homo sapiens 9-12 18338235-2 2008 N-Carbamylglutamate, a NAG analogue, has been reported to correct hyperammonaemia in neonates with organic acidaemias. N-carbamylglutamate 0-19 N-acetyl-alpha-glucosaminidase Homo sapiens 23-26 20303810-9 2010 For either condition, N-carbamylglutamate (NCG), a stable functional analog of NAG, was found to either restore or improve the deficient urea-cycle function. N-carbamylglutamate 22-41 N-acetyl-alpha-glucosaminidase Homo sapiens 79-82 15050968-10 2004 A structural analog of NAG, carbamylglutamate, has been shown to bind and activate CPSI, and several patients have been reported to respond favorably to this drug (Carbaglu). N-carbamylglutamate 28-45 N-acetyl-alpha-glucosaminidase Homo sapiens 23-26