PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15878998-7	2005	This compound could be visualized on aortic endothelial cells, and its binding could be prevented by rauwolscine, providing direct evidence for the presence of alpha(2)-adrenoceptors on the endothelium.	Yohimbine	101-112	adrenergic receptor, alpha 2a	Mus musculus	160-182	
17115069-12	2007	Blockade of alpha(2)-adrenoceptors (1 microM rauwolscine) increased these purinergic pressor responses to 296+/-112% (1 Hz) in WT but not in alpha(2A)-KO mice.	Yohimbine	45-56	adrenergic receptor, alpha 2a	Mus musculus	12-34	
12721093-14	2003	Rauwolscine and phentolamine increased tritium overflow evoked by 120 pulses at 3 Hz up to seven-fold in WT and alpha(2B)KO tissues, three-fold in alpha(2A)KO and alpha(2C)KO tissues, and two-fold in alpha(2AC)KO tissues.	Yohimbine	0-11	adrenergic receptor, alpha 2a	Mus musculus	147-155	
11818770-8	2002	The alpha2-adrenoceptor antagonist yohimbine inhibited isoflurane antinociception, and this effect was mediated by spinal alpha2 adrenoceptors.	Yohimbine	35-44	adrenergic receptor, alpha 2a	Mus musculus	122-142	
19225179-5	2009	To identify the alpha(2)AR subtype involved, equilibrium dissociation constants (pK(b)) were determined for the selective alphaAR antagonists atipamezole (8.79), rauwolscine (7.75), 2-(2,6-dimethoxyphenoxyethyl)aminomethyl-1,4-benzodioxane hydrochloride (WB-4101; 6.87), and prazosin (5.71).	Yohimbine	162-173	adrenergic receptor, alpha 2a	Mus musculus	16-26	
32741943-9	2020	Moreover, the positive effects of oxymetazoline were attenuated by yohimbine and BRL44408, which are selective alpha2- and alpha2A-adrenoceptor antagonists, respectively.	Yohimbine	67-76	adrenergic receptor, alpha 2a	Mus musculus	123-143	
23691077-0	2013	Yohimbine promotes cardiac NE release and prevents LPS-induced cardiac dysfunction via blockade of presynaptic alpha2A-adrenergic receptor.	Yohimbine	0-9	adrenergic receptor, alpha 2a	Mus musculus	111-138	
23691077-5	2013	Immunohistochemical analysis revealed that cardiac alpha2A-AR was mostly located in sympathetic nerve presynaptic membrane; YHB decreased cardiac alpha2A-AR level and promoted cardiac norepinephrine (NE) release in endotoxemic mice.	Yohimbine	124-127	adrenergic receptor, alpha 2a	Mus musculus	51-61	
23691077-5	2013	Immunohistochemical analysis revealed that cardiac alpha2A-AR was mostly located in sympathetic nerve presynaptic membrane; YHB decreased cardiac alpha2A-AR level and promoted cardiac norepinephrine (NE) release in endotoxemic mice.	Yohimbine	124-127	adrenergic receptor, alpha 2a	Mus musculus	146-156	
23691077-10	2013	Altogether, these findings indicate that YHB attenuates LPS-induced cardiac dysfunction, at least in part, through blocking presynaptic alpha2A-AR and thus increasing cardiac NE release.	Yohimbine	41-44	adrenergic receptor, alpha 2a	Mus musculus	136-146	
18772254-6	2008	Moreover, alpha(2A)-AR knockout mice exhibited similar cocaine CPP extinction and exacerbated extinction impairing effects of yohimbine.	Yohimbine	126-135	adrenergic receptor, alpha 2a	Mus musculus	10-22