PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9915824-6 1999 In fibroblasts, insulin increased the enzymatic activity of GGTase II 2.5-fold after 1 h of incubation, an effect that is blocked by perillyl alcohol, an inhibitor of prenyltransferases, but not by the geranylgeranyltransferase I inhibitor, GGTI-298, or the farnesyltransferase inhibitor, alpha-hydroxyfarnesylphosphonic acid. GGTI 298 241-249 insulin Homo sapiens 16-23