PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1038-0	1975	Beef liver L-Glutamate dehydrogenase mechanism: presteady state study of the catalytic reduction of 2.oxoglutarate by NADPH.	Ketoglutaric Acids	100-114	2,4-dienoyl-CoA reductase 1	Homo sapiens	118-123	
38020-6	1979	11, 421 (1973)] of the Kirstein reaction, which depends on the catalytic amination of alpha-ketoglutarate by the action of glutamate dehydrogenase with NADPH as the cofactor instead of NADH.	Ketoglutaric Acids	86-105	2,4-dienoyl-CoA reductase 1	Homo sapiens	152-157	
21049082-7	2010	By feeding the cells labeled glutamine, we also detected a "backwards" flux in the tricarboxylic acid cycle from alpha-ketoglutarate to citrate that was enhanced in contact-inhibited fibroblasts; this flux likely contributes to shuttling of NADPH from the mitochondrion to cytosol for redox defense or fatty acid synthesis.	Ketoglutaric Acids	113-132	2,4-dienoyl-CoA reductase 1	Homo sapiens	241-246	
14526024-4	2003	Anaerobic growth on aromatic compounds induced 2-oxoglutarate:acceptor oxidoreductase (KGOR), which specifically reduced NADP(+), and NADPH:acceptor oxidoreductase.	Ketoglutaric Acids	47-61	2,4-dienoyl-CoA reductase 1	Homo sapiens	134-139	
32729927-1	2020	Isocitrate dehydrogenase 1 (IDH1) catalyzes the reversible NADP+-dependent conversion of isocitrate to alpha-ketoglutarate (alphaKG) to provide critical cytosolic substrates and drive NADPH-dependent reactions like lipid biosynthesis and glutathione regeneration.	Ketoglutaric Acids	103-122	2,4-dienoyl-CoA reductase 1	Homo sapiens	184-189	
31478653-1	2019	Human isocitrate dehydrogenase 1 (HsICDH1) is a cytoplasmic homodimeric Mg(II)-dependent enzyme that converts d-isocitrate (D-ICT) and NADP+ to alpha-ketoglutarate (AKG), CO2, and NADPH.	Ketoglutaric Acids	144-163	2,4-dienoyl-CoA reductase 1	Homo sapiens	180-185	
32777735-3	2020	Cancer-associated substitutions in IDH1 and IDH2 impair wild-type production of 2-oxoglutarate and reduced nicotinamide adenine dinucleotide phosphate (NADPH) from isocitrate and oxidised nicotinamide adenine dinucleotide phosphate (NADP+ ), and substantially promote the IDH variant catalysed conversion of 2-oxoglutarate to d-2-hydroxyglutarate (d-2HG).	Ketoglutaric Acids	308-322	2,4-dienoyl-CoA reductase 1	Homo sapiens	107-158	
32777735-3	2020	Cancer-associated substitutions in IDH1 and IDH2 impair wild-type production of 2-oxoglutarate and reduced nicotinamide adenine dinucleotide phosphate (NADPH) from isocitrate and oxidised nicotinamide adenine dinucleotide phosphate (NADP+ ), and substantially promote the IDH variant catalysed conversion of 2-oxoglutarate to d-2-hydroxyglutarate (d-2HG).	Ketoglutaric Acids	308-322	2,4-dienoyl-CoA reductase 1	Homo sapiens	107-151	
27422263-2	2017	1.4.1.3) is a mitochondrial enzyme that catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia while reducing NAD+ and/or NADP+ to NADH and/or NADPH.	Ketoglutaric Acids	103-122	2,4-dienoyl-CoA reductase 1	Homo sapiens	183-188	
22442146-1	2012	Isocitrate dehydrogenase (IDH) is a reversible enzyme that catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (ICT) to alpha-ketoglutarate (alphaKG) and the NADPH/CO(2)-dependent reductive carboxylation of alphaKG to ICT.	Ketoglutaric Acids	140-159	2,4-dienoyl-CoA reductase 1	Homo sapiens	178-183