PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29456710-0 2018 Mechanism of apoptosis induction associated with ERK1/2 upregulation via goniothalamin in melanoma cells. goniothalamin 73-86 mitogen-activated protein kinase 3 Homo sapiens 49-55 29456710-10 2018 These results suggest that goniothalamin has an effect, as anti-proliferation and apoptosis induction in A375 cells were associated with upregulated p-ERK1/2, c-Jun and downregulated p-PDK1 (Ser241), p-Akt (Ser473) in A375 cells. goniothalamin 27-40 mitogen-activated protein kinase 3 Homo sapiens 151-157 26987063-5 2016 In addition, goniothalamin induced apoptosis via p-JNK1/2 and p-p38 upregulation and inhibited cell survival via p-ERK1/2 and p-Akt downregulation. goniothalamin 13-26 mitogen-activated protein kinase 3 Homo sapiens 115-121 26987063-0 2016 Goniothalamin induces apoptosis associated with autophagy activation through MAPK signaling in SK-BR-3 cells. goniothalamin 0-13 mitogen-activated protein kinase 3 Homo sapiens 77-81