PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26209973-8	2015	Moreover, Fe transport-related genes (NtPIC1, NtNRAMP1, and NtFER1) were upregulated in NtPIC1-OE plants, while Fe deficiency-related genes (NtFRO1, NtIRT1, and NtZIP1) that mediate Cd uptake were downregulated.	Cadmium	182-184	protein TIC 21, chloroplastic-like	Nicotiana tabacum	88-94	
26209973-9	2015	We also found that the activities of several antioxidative enzymes were significantly higher in NtPIC1-OE plants than in WT plants under Cd stress.	Cadmium	137-139	protein TIC 21, chloroplastic-like	Nicotiana tabacum	96-102	
26209973-0	2015	Overexpression of the iron transporter NtPIC1 in tobacco mediates tolerance to cadmium.	Cadmium	79-86	protein TIC 21, chloroplastic-like	Nicotiana tabacum	39-45	
26209973-10	2015	Overall, our results demonstrate that overexpression of NtPIC1 is an efficient way to increase shoot Fe concentrations and reduce Cd uptake/accumulation in plants.	Cadmium	130-132	protein TIC 21, chloroplastic-like	Nicotiana tabacum	56-62	
26209973-1	2015	KEY MESSAGE: Overexpression of the iron transporter NtPIC1 increases iron concentration in shoots and reduces Cd uptake/accumulation in plants, mediating tolerance to cadmium.	Cadmium	110-112	protein TIC 21, chloroplastic-like	Nicotiana tabacum	52-58	
26209973-1	2015	KEY MESSAGE: Overexpression of the iron transporter NtPIC1 increases iron concentration in shoots and reduces Cd uptake/accumulation in plants, mediating tolerance to cadmium.	Cadmium	167-174	protein TIC 21, chloroplastic-like	Nicotiana tabacum	52-58	
26209973-4	2015	Based on preliminary results in transformed Saccharomyces cerevisiae BY4741 cells, which showed that NtPIC1 expression increased Cd tolerance, this study evaluated Cd tolerance in tobacco plants overexpressing NtPIC1 (NtPIC1-OE).	Cadmium	129-131	protein TIC 21, chloroplastic-like	Nicotiana tabacum	101-107	
26209973-6	2015	Under Cd stress, WT plants display more chlorosis, stronger growth inhibition, and lower chlorophyll concentrations than NtPIC1-OE plants.	Cadmium	6-8	protein TIC 21, chloroplastic-like	Nicotiana tabacum	121-127	
26209973-7	2015	Importantly, NtPIC1-OE plants had higher Fe concentrations in shoots and lower Fe concentrations in roots, and Cd concentrations in NtPIC1-OE plants were significantly lower compared to those in WT plants.	Cadmium	111-113	protein TIC 21, chloroplastic-like	Nicotiana tabacum	132-138