PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25291725-1	2014	Suvorexant is a pharmacologically novel dual antagonist of orexin receptors OX1R and OX2R, which has an effect that promotes sleep by reducing arousal and wakefulness.	suvorexant	0-10	hypocretin receptor 2	Homo sapiens	85-89	
29450984-4	2018	By comparison with the wild type of OX2 R, the results show the 1,2,3-triazole and p-toluamide groups of suvorexant are changed in the N324A mutant of OX2 R during 200 ns MD simulations.	suvorexant	105-115	hypocretin receptor 2	Homo sapiens	36-41	
29450984-4	2018	By comparison with the wild type of OX2 R, the results show the 1,2,3-triazole and p-toluamide groups of suvorexant are changed in the N324A mutant of OX2 R during 200 ns MD simulations.	suvorexant	105-115	hypocretin receptor 2	Homo sapiens	151-156	
29450984-5	2018	The QM/MM and weak interaction analysis are employed to calculate the non-covalent bonds interaction between suvorexant and key residues in the wild type and N324A mutant of OX2 R.	suvorexant	109-119	hypocretin receptor 2	Homo sapiens	174-179	
25533960-3	2015	The human OX2 receptor (OX2R) belongs to the beta branch of the rhodopsin family of GPCRs, and can bind to diverse compounds including the native agonist peptides orexin-A and orexin-B and the potent therapeutic inhibitor suvorexant.	suvorexant	222-232	hypocretin receptor 2	Homo sapiens	10-22	
25533960-3	2015	The human OX2 receptor (OX2R) belongs to the beta branch of the rhodopsin family of GPCRs, and can bind to diverse compounds including the native agonist peptides orexin-A and orexin-B and the potent therapeutic inhibitor suvorexant.	suvorexant	222-232	hypocretin receptor 2	Homo sapiens	24-28