PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34456739-0 2021 Rutin, A Natural Inhibitor of IGPD Protein, Partially Inhibits Biofilm Formation in Staphylococcus xylosus ATCC700404 in vitro and in vivo. Rutin 0-5 imidazoleglycerol-phosphate dehydratase HisB Staphylococcus xylosus 30-34 34456739-3 2021 Here, we confirmed that rutin can effectively inhibit biofilm formation in S. xylosus, of which the inhibition mechanism involves its ability to interact with imidazole glycerol phosphate dehydratase (IGPD), a key enzyme in the process of biofilm formation. Rutin 24-29 imidazoleglycerol-phosphate dehydratase HisB Staphylococcus xylosus 159-199 34456739-3 2021 Here, we confirmed that rutin can effectively inhibit biofilm formation in S. xylosus, of which the inhibition mechanism involves its ability to interact with imidazole glycerol phosphate dehydratase (IGPD), a key enzyme in the process of biofilm formation. Rutin 24-29 imidazoleglycerol-phosphate dehydratase HisB Staphylococcus xylosus 201-205 34456739-7 2021 Meanwhile, the results from molecular dynamic simulation and Bio-layer interferometry (BLI) technique showed that rutin could bind to IGPD strongly. Rutin 114-119 imidazoleglycerol-phosphate dehydratase HisB Staphylococcus xylosus 134-138