PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24285294-8 2014 The Km value of E-3-S for OATP2B1 in the presence of rutin (9.21 mum) was almost the same as that in the absence of rutin (8.53 mum). Rutin 53-58 solute carrier organic anion transporter family member 2B1 Homo sapiens 26-33 24285294-6 2014 Rutin stimulated the uptake of estrone-3-sulfate (E-3-S), taurocholic acid (TCA), cholic acid (CA) and rosuvastatin by OATP2B1, but not p-coumaric acid or ferulic acid. Rutin 0-5 solute carrier organic anion transporter family member 2B1 Homo sapiens 119-126 24285294-7 2014 The EC50 of rutin for transport by OATP2B1 was 2.32 mum. Rutin 12-17 solute carrier organic anion transporter family member 2B1 Homo sapiens 35-42 24285294-9 2014 On the other hand, the Vmax of E-3-S transport by OATP2B1 in the presence of rutin (270 pmol/mg protein/min) was 1.2-fold higher than that in the absence of rutin (218 pmol/mg protein/min). Rutin 77-82 solute carrier organic anion transporter family member 2B1 Homo sapiens 50-57 24285294-9 2014 On the other hand, the Vmax of E-3-S transport by OATP2B1 in the presence of rutin (270 pmol/mg protein/min) was 1.2-fold higher than that in the absence of rutin (218 pmol/mg protein/min). Rutin 157-162 solute carrier organic anion transporter family member 2B1 Homo sapiens 50-57 24285294-10 2014 Moreover, the expression level of OATP2B1 on the cell membrane was increased by treatment with rutin for 5 min without alteration of the total OATP2B1 expression level. Rutin 95-100 solute carrier organic anion transporter family member 2B1 Homo sapiens 34-41 24285294-12 2014 The stimulatory effect of rutin is a little weak but may affect the absorption of OATP2B1 substrates, because rutin is taken daily in foods and its intestinal concentration would reach the stimulatory range of OATP2B1. Rutin 26-31 solute carrier organic anion transporter family member 2B1 Homo sapiens 82-89 24285294-12 2014 The stimulatory effect of rutin is a little weak but may affect the absorption of OATP2B1 substrates, because rutin is taken daily in foods and its intestinal concentration would reach the stimulatory range of OATP2B1. Rutin 26-31 solute carrier organic anion transporter family member 2B1 Homo sapiens 210-217 24285294-12 2014 The stimulatory effect of rutin is a little weak but may affect the absorption of OATP2B1 substrates, because rutin is taken daily in foods and its intestinal concentration would reach the stimulatory range of OATP2B1. Rutin 110-115 solute carrier organic anion transporter family member 2B1 Homo sapiens 82-89 24285294-12 2014 The stimulatory effect of rutin is a little weak but may affect the absorption of OATP2B1 substrates, because rutin is taken daily in foods and its intestinal concentration would reach the stimulatory range of OATP2B1. Rutin 110-115 solute carrier organic anion transporter family member 2B1 Homo sapiens 210-217