PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22802261-0 2012 The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment. Epirubicin 64-74 MAPK activated protein kinase 2 Homo sapiens 13-16 31537377-5 2019 Epirubicin induces activation of p38-MK2 signaling pathway to phosphorylate gp130 at Ser 782, which results in gp130 internalization and degradation by lysosome. Epirubicin 0-10 MAPK activated protein kinase 2 Homo sapiens 37-40 22802261-8 2012 In addition, the p38-MK2 axis can also limit c-jun-NH(2)-kinase (JNK) induction by epirubicin and, notably, JNK represses FOXM1 expression. Epirubicin 83-93 MAPK activated protein kinase 2 Homo sapiens 21-24 22802261-9 2012 Collectively, these findings underscore the importance of p38-MK2 signaling in the control of E2F1 and FOXM1 expression as well as epirubicin sensitivity. Epirubicin 131-141 MAPK activated protein kinase 2 Homo sapiens 62-65