PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31769755-4 2019 Using siRNA combined with lipidomics and membrane fluidity assays (FRAP and Laurdan dye staining) we further show that the human ACSL1 potentiates lipotoxicity by the saturated fatty acid palmitate: silencing ACSL1 protects against the membrane rigidifying effects of palmitate and acts as a suppressor of AdipoR2 knockdown, thus echoing the C. elegans findings. saturated fatty acid palmitate 167-197 acyl-CoA synthetase long chain family member 1 Homo sapiens 129-134 31769755-4 2019 Using siRNA combined with lipidomics and membrane fluidity assays (FRAP and Laurdan dye staining) we further show that the human ACSL1 potentiates lipotoxicity by the saturated fatty acid palmitate: silencing ACSL1 protects against the membrane rigidifying effects of palmitate and acts as a suppressor of AdipoR2 knockdown, thus echoing the C. elegans findings. saturated fatty acid palmitate 167-197 acyl-CoA synthetase long chain family member 1 Homo sapiens 209-214