PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23824011-0 2013 (-)-Xanthatin induces the prolonged expression of c-Fos through an N-acetyl-L-cysteine (NAC)-sensitive mechanism in human breast cancer MDA-MB-231 cells. xanthatin 0-13 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 50-55 23824011-5 2013 After the exposure of breast cancer cells to (-)-xanthatin or etoposide, a prolonged and marked up-regulation in the expression of c-fos, a proapoptotic molecule, was detected together with GADD45gamma; and the expression of these molecules was stabilized by ROS and abrogated by the pretreatment with N-acetyl-L-cysteine (NAC), a potent ROS scavenger. xanthatin 45-58 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 131-136 23824011-6 2013 (-)-Xanthatin in particular exhibited stronger anti-proliferative potential than that of etoposide, which underlies the marked induction of c-fos/GADD45gamma and ROS production. xanthatin 0-13 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 140-145