PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31673231-6 2019 Combined treatment of TRAIL with bortezomib resulted in strong synergistic response with enhanced activation of caspases-8, -9 and -3, and increased Annexin V-binding cell fractions in TRAIL-resistant SNU-216 cells. bortezomib 33-43 TNF superfamily member 10 Homo sapiens 22-27 31673231-6 2019 Combined treatment of TRAIL with bortezomib resulted in strong synergistic response with enhanced activation of caspases-8, -9 and -3, and increased Annexin V-binding cell fractions in TRAIL-resistant SNU-216 cells. bortezomib 33-43 TNF superfamily member 10 Homo sapiens 185-190 31673231-12 2019 In summary, upregulation of DR5 by bortezomib is of critical significance in the synergy of bortezomib with TRAIL in apoptosis of TRAIL-resistant SNU-216 and that activity of ERK1/2 is required in the bortezomib-induced DR5 overexpression. bortezomib 35-45 TNF superfamily member 10 Homo sapiens 108-113 31673231-12 2019 In summary, upregulation of DR5 by bortezomib is of critical significance in the synergy of bortezomib with TRAIL in apoptosis of TRAIL-resistant SNU-216 and that activity of ERK1/2 is required in the bortezomib-induced DR5 overexpression. bortezomib 35-45 TNF superfamily member 10 Homo sapiens 130-135 31673231-12 2019 In summary, upregulation of DR5 by bortezomib is of critical significance in the synergy of bortezomib with TRAIL in apoptosis of TRAIL-resistant SNU-216 and that activity of ERK1/2 is required in the bortezomib-induced DR5 overexpression. bortezomib 92-102 TNF superfamily member 10 Homo sapiens 130-135 31673231-12 2019 In summary, upregulation of DR5 by bortezomib is of critical significance in the synergy of bortezomib with TRAIL in apoptosis of TRAIL-resistant SNU-216 and that activity of ERK1/2 is required in the bortezomib-induced DR5 overexpression. bortezomib 92-102 TNF superfamily member 10 Homo sapiens 130-135