PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32007561-8 2020 Docking of 11OHP4, 11KP4 and the 5alpha-reduced metabolites, 5alpha-pregnan-11beta-ol-3,20-dione (11OH-DHP4) and 5alpha-pregnan-3,11,20-trione (11K-DHP4) with human CYP17A1 showed minimal changes in the orientation of these C11-oxy C21 steroids in the active pocket when compared with the binding of progesterone suggesting the 17,20-lyase is impaired by the C11-hydroxyl and keto moieties. bis-valerato-oxalato-1,2-diaminocyclohexaneplatinum 11-17 aldo-keto reductase family 1 member C4 Homo sapiens 224-227 32007561-8 2020 Docking of 11OHP4, 11KP4 and the 5alpha-reduced metabolites, 5alpha-pregnan-11beta-ol-3,20-dione (11OH-DHP4) and 5alpha-pregnan-3,11,20-trione (11K-DHP4) with human CYP17A1 showed minimal changes in the orientation of these C11-oxy C21 steroids in the active pocket when compared with the binding of progesterone suggesting the 17,20-lyase is impaired by the C11-hydroxyl and keto moieties. bis-valerato-oxalato-1,2-diaminocyclohexaneplatinum 11-17 aldo-keto reductase family 1 member C4 Homo sapiens 359-362