PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26977879-5	2016	Moreover, nelfinavir is effective in BRAF and NRAS mutant melanoma cells isolated from patients progressed on MAPK inhibitor (MAPKi) therapy and in BRAF/NRAS/PTEN mutant tumors.	Nelfinavir	10-20	phosphatase and tensin homolog	Homo sapiens	158-162	
17483362-0	2007	Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.	Nelfinavir	152-162	phosphatase and tensin homolog	Homo sapiens	0-32	
17483362-4	2007	Nelfinavir decreased Akt phosphorylation and enhanced radiosensitization in U251MG and U87MG glioblastoma cells, both of which are PTEN deficient.	Nelfinavir	0-10	phosphatase and tensin homolog	Homo sapiens	131-135	
17483362-5	2007	In the derivative line U251MG-PTEN, induction of wild-type PTEN with doxycycline decreased P-Akt expression and increased radiosensitivity to a similar extent as nelfinavir.	Nelfinavir	162-172	phosphatase and tensin homolog	Homo sapiens	59-63	
28137980-10	2017	NFV (20 microM) decreased the levels of total and p-AKT in PTEN-deficient FTC133 cells.	Nelfinavir	0-3	phosphatase and tensin homolog	Homo sapiens	59-63