PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31838577-9 2020 Nelfinavir and lopinavir, two clinically approved HIV protease inhibitors, promote eIF2alpha phosphorylation by different mechanisms. Nelfinavir 0-10 eukaryotic translation initiation factor 2A Homo sapiens 83-92 26715744-6 2016 Mechanistically, Nelfinavir-mediated ISR bypassed direct activation of the eIF2alpha stress kinases and instead relied on the inhibition of the constitutive eIF2alpha dephosphorylation and down-regulation of the phophatase cofactor CReP (Constitutive Repressor of eIF2alpha Phosphorylation; also known as PPP1R15B). Nelfinavir 17-27 eukaryotic translation initiation factor 2A Homo sapiens 75-84 26715744-6 2016 Mechanistically, Nelfinavir-mediated ISR bypassed direct activation of the eIF2alpha stress kinases and instead relied on the inhibition of the constitutive eIF2alpha dephosphorylation and down-regulation of the phophatase cofactor CReP (Constitutive Repressor of eIF2alpha Phosphorylation; also known as PPP1R15B). Nelfinavir 17-27 eukaryotic translation initiation factor 2A Homo sapiens 157-166