PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30868140-4 2018 Here we show that DREADD agonist 21 (C21) (11-(1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine) is a potent and selective agonist at both excitatory (hM3Dq) and inhibitory (hM4Di) DREADDs and has excellent bioavailability, pharmacokinetic properties, and brain penetrability. hm3dq 147-152 TBL1X/Y related 1 Homo sapiens 37-40