PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16844679-4 2006 We hypothesized that Marimastat, a broad-spectrum MMP and TNF-alpha converting enzyme (TACE) inhibitor, might modulate this injury through interruption of inflammatory pathways. marimastat 21-31 a disintegrin and metallopeptidase domain 17 Mus musculus 58-85 20593020-4 2010 We hypothesized that treatment with a broad-spectrum MMP and TACE-inhibitor (Marimastat) would ameliorate injury and inflammation, leading to decreased fibrogenesis during repeated hepatotoxin-induced liver injury. marimastat 77-87 a disintegrin and metallopeptidase domain 17 Mus musculus 61-65 21980496-3 2011 We hypothesized that treatment with the pharmacologic tumor necrosis factor-alpha converting enzyme (TACE)-inhibitor Marimastat would reverse established steatosis, leading to improved outcome following hepatectomy. marimastat 117-127 a disintegrin and metallopeptidase domain 17 Mus musculus 54-99 21980496-3 2011 We hypothesized that treatment with the pharmacologic tumor necrosis factor-alpha converting enzyme (TACE)-inhibitor Marimastat would reverse established steatosis, leading to improved outcome following hepatectomy. marimastat 117-127 a disintegrin and metallopeptidase domain 17 Mus musculus 101-105 21980496-12 2011 CONCLUSION/SIGNIFICANCE: Treatment with the TACE-inhibitor Marimastat improved surrogate markers for insulin sensitivity and reversed steatosis in mouse models of diet-induced obesity and leptin deficiency, thereby attenuating post-operative injury following hepatectomy. marimastat 59-69 a disintegrin and metallopeptidase domain 17 Mus musculus 44-48 16844679-4 2006 We hypothesized that Marimastat, a broad-spectrum MMP and TNF-alpha converting enzyme (TACE) inhibitor, might modulate this injury through interruption of inflammatory pathways. marimastat 21-31 a disintegrin and metallopeptidase domain 17 Mus musculus 87-91