PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20869730-3 2010 A homozygous missense mutation, causing a substitution of a molecule of arginine for histidine at the helicase domain of the senataxin protein, was found. Arginine 72-80 senataxin Homo sapiens 125-134 15732101-5 2005 We have identified four mutations in senataxin in the French-Canadian population including two novel missense mutations: the 5927T-->G mutation changes the leucine encoded by codon 1976 to an arginine in the helicase domain (L1976R), and the 193G-->A mutation changes a glutamic acid encoded by codon 65 into a lysine in the N-terminal domain of the protein (E65K). Arginine 195-203 senataxin Homo sapiens 37-46