PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28545736-4	2017	Much like IDO1, arginase 1 (Arg1) is an immunoregulatory enzyme that catalyzes the degradation of arginine.	Arginine	98-106	indoleamine 2,3-dioxygenase 1	Homo sapiens	10-14	
33025106-6	2021	Moreover, immunosuppressive cells suppress the function of effector immune cells by catabolizing L-arginine and tryptophan through the activation of arginase 1 (ARG1) and indoleamine 2,3-dioxygenase (IDO), respectively.	Arginine	97-107	indoleamine 2,3-dioxygenase 1	Homo sapiens	171-198	
33025106-6	2021	Moreover, immunosuppressive cells suppress the function of effector immune cells by catabolizing L-arginine and tryptophan through the activation of arginase 1 (ARG1) and indoleamine 2,3-dioxygenase (IDO), respectively.	Arginine	97-107	indoleamine 2,3-dioxygenase 1	Homo sapiens	200-203	
30797943-4	2019	We examined here current knowledge of indoleamine 2,3-dioxygenase 1 (IDO1) and arginase 1 (ARG1), the main enzymes catabolizing tryptophan and arginine, respectively, in organ-specific and systemic autoimmune diseases as well as in the development of autoantibodies to therapeutic proteins.	Arginine	143-151	indoleamine 2,3-dioxygenase 1	Homo sapiens	38-67	
30797943-4	2019	We examined here current knowledge of indoleamine 2,3-dioxygenase 1 (IDO1) and arginase 1 (ARG1), the main enzymes catabolizing tryptophan and arginine, respectively, in organ-specific and systemic autoimmune diseases as well as in the development of autoantibodies to therapeutic proteins.	Arginine	143-151	indoleamine 2,3-dioxygenase 1	Homo sapiens	69-73	
30696923-6	2019	Indoleamine 2,3 dioxygenase (IDO) and arginase 1 (ARG1), which catabolize Trp and Arg, respectively, respond to inflammatory cues including interferons and transforming growth factor-beta (TGFbeta) cytokines.	Arginine	82-85	indoleamine 2,3-dioxygenase 1	Homo sapiens	0-27	
30696923-6	2019	Indoleamine 2,3 dioxygenase (IDO) and arginase 1 (ARG1), which catabolize Trp and Arg, respectively, respond to inflammatory cues including interferons and transforming growth factor-beta (TGFbeta) cytokines.	Arginine	82-85	indoleamine 2,3-dioxygenase 1	Homo sapiens	29-32	
28214225-1	2017	Arginase 1 (Arg1) and indoleamine 2,3-dioxygenase 1 (IDO1) are immunoregulatory enzymes catalyzing the degradation of l-arginine and l-tryptophan, respectively, resulting in local amino acid deprivation.	Arginine	118-128	indoleamine 2,3-dioxygenase 1	Homo sapiens	22-51	
28214225-1	2017	Arginase 1 (Arg1) and indoleamine 2,3-dioxygenase 1 (IDO1) are immunoregulatory enzymes catalyzing the degradation of l-arginine and l-tryptophan, respectively, resulting in local amino acid deprivation.	Arginine	118-128	indoleamine 2,3-dioxygenase 1	Homo sapiens	53-57	
22897519-2	2012	Indoleamine 2,3-dioxygenase (IDO) and arginase type I (ARG) catabolize tryptophane and arginine, respectively, and exert proapoptotic and antiproliferative effects on T-cells.	Arginine	87-95	indoleamine 2,3-dioxygenase 1	Homo sapiens	0-27	
22897519-2	2012	Indoleamine 2,3-dioxygenase (IDO) and arginase type I (ARG) catabolize tryptophane and arginine, respectively, and exert proapoptotic and antiproliferative effects on T-cells.	Arginine	87-95	indoleamine 2,3-dioxygenase 1	Homo sapiens	29-32	
16797727-9	2006	However, in monocyte-derived macrophages, with a higher NO production, aminoguanidine increased IDO activity, but the NOS substrate arginine decreased IDO activity.	Arginine	132-140	indoleamine 2,3-dioxygenase 1	Homo sapiens	151-154	
22082147-2	2011	While human IDO is able to oxidize both L- and D-Trp, human TDO (hTDO) displays major specificity for L-Trp.	Arginine	40-42	indoleamine 2,3-dioxygenase 1	Homo sapiens	12-15