PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24204381-5	2013	When co-stimulated with 15d-PGJ2 and activin, 15d-PGJ2 inhibited the activin-induced increases in ActR and Smad expression, and decreased activin-induced IL-6 production.	15-deoxy-delta(12,14)-prostaglandin J2	24-32	interleukin 6	Homo sapiens	154-158	
24204381-5	2013	When co-stimulated with 15d-PGJ2 and activin, 15d-PGJ2 inhibited the activin-induced increases in ActR and Smad expression, and decreased activin-induced IL-6 production.	15-deoxy-delta(12,14)-prostaglandin J2	46-54	interleukin 6	Homo sapiens	154-158	
24204381-8	2013	These results suggest that 15d-PGJ2 suppresses activin-induced ActR and Smad expression, down-regulates IL-6 production, and up-regulates IL-8 production via suppression of NF- kappa B and MAPK signaling pathway in HepG2 cells.	15-deoxy-delta(12,14)-prostaglandin J2	27-35	interleukin 6	Homo sapiens	104-108	
27190500-3	2016	The supernatant culture medium of the TPC-1 cells that was treated either with 15d-PGJ2 or with vehicle (control) for 24 hours was assessed for IL-6 secretion via CBA assay.	15-deoxy-delta(12,14)-prostaglandin J2	79-87	interleukin 6	Homo sapiens	144-148	
27190500-5	2016	TPC-1 cells treated with 15d-PGJ2 decreased the secretion and expression of IL-6 and STAT3, while it increased SOCS1 and SOCS3.	15-deoxy-delta(12,14)-prostaglandin J2	25-33	interleukin 6	Homo sapiens	76-80	
27190500-6	2016	Overall, we demonstrated that 15d-PGJ2 downregulated IL-6 signaling pathway and led TPC-1 cells into apoptosis.	15-deoxy-delta(12,14)-prostaglandin J2	30-38	interleukin 6	Homo sapiens	53-57	
16155367-9	2005	The two new PPAR-gamma agonists and 15d-PGJ2 also inhibited TNF-alpha-induced interleukin-6 (IL-6) and monocyte chemoattractant protein-1 (MCP-1) production in supernatants of TNF-alpha-stimulated ECs, whereas ciglitazone and DIM-C-pPhCH(3) did not decrease TNF-alpha-induced expression of these two proteins.	15-deoxy-delta(12,14)-prostaglandin J2	36-44	interleukin 6	Homo sapiens	78-91	
16155367-9	2005	The two new PPAR-gamma agonists and 15d-PGJ2 also inhibited TNF-alpha-induced interleukin-6 (IL-6) and monocyte chemoattractant protein-1 (MCP-1) production in supernatants of TNF-alpha-stimulated ECs, whereas ciglitazone and DIM-C-pPhCH(3) did not decrease TNF-alpha-induced expression of these two proteins.	15-deoxy-delta(12,14)-prostaglandin J2	36-44	interleukin 6	Homo sapiens	93-97	
15840591-7	2005	Inhibition was not specific for IL-10, as induction of STAT activation by IFN-gamma and IL-6 was also inhibited by 15d-PGJ2.	15-deoxy-delta(12,14)-prostaglandin J2	115-123	interleukin 6	Homo sapiens	88-92