PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25681332-3 2015 We report that the eicosanoid 15-deoxy-Delta(12,14)-PGJ2 (15d-PGJ2) and related cyclopentenone PGs inhibit caspase-1 activation by the NLR family leucine-rich repeat protein (NLRP)1 and NLRP3 inflammasomes. 15-deoxy-delta(12,14)-prostaglandin J2 30-56 caspase 1 Mus musculus 107-116 25681332-3 2015 We report that the eicosanoid 15-deoxy-Delta(12,14)-PGJ2 (15d-PGJ2) and related cyclopentenone PGs inhibit caspase-1 activation by the NLR family leucine-rich repeat protein (NLRP)1 and NLRP3 inflammasomes. 15-deoxy-delta(12,14)-prostaglandin J2 58-66 caspase 1 Mus musculus 107-116 25681332-5 2015 Instead, 15d-PGJ2 prevents the autoproteolytic activation of caspase-1 and the maturation of IL-1beta through induction of a cellular state inhibitory to caspase-1 proteolytic function. 15-deoxy-delta(12,14)-prostaglandin J2 9-17 caspase 1 Mus musculus 61-70 25681332-5 2015 Instead, 15d-PGJ2 prevents the autoproteolytic activation of caspase-1 and the maturation of IL-1beta through induction of a cellular state inhibitory to caspase-1 proteolytic function. 15-deoxy-delta(12,14)-prostaglandin J2 9-17 caspase 1 Mus musculus 154-163