PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21771726-5 2011 Among all studied HDAC inhibitors, valproic acid (VPA) and CI-994 showed prolonged effects on histone acetylation, while combination with decitabine produced the most prominent effects on caspase-8 re-expression. tacedinaline 59-65 histone deacetylase 9 Homo sapiens 18-22 32599645-4 2020 Here, we describe that TW9, a newly generated adduct of the BET inhibitor (+)-JQ1 and class I HDAC inhibitor CI994, is a potent dual inhibitor simultaneously targeting BET and HDAC proteins. tacedinaline 109-114 histone deacetylase 9 Homo sapiens 94-98 32599645-4 2020 Here, we describe that TW9, a newly generated adduct of the BET inhibitor (+)-JQ1 and class I HDAC inhibitor CI994, is a potent dual inhibitor simultaneously targeting BET and HDAC proteins. tacedinaline 109-114 histone deacetylase 9 Homo sapiens 176-180 25827403-2 2015 An innovative aspect of this drug delivery particle lies in the NP conjugation of a histone deacetylase (HDAC) inhibitor, CI-994 (Tacedinaline), introduced with a clickable acid-responsive prodrug during monomer synthesis, prior to polymerization. tacedinaline 122-128 histone deacetylase 9 Homo sapiens 84-103 25827403-2 2015 An innovative aspect of this drug delivery particle lies in the NP conjugation of a histone deacetylase (HDAC) inhibitor, CI-994 (Tacedinaline), introduced with a clickable acid-responsive prodrug during monomer synthesis, prior to polymerization. tacedinaline 122-128 histone deacetylase 9 Homo sapiens 105-109 25827403-2 2015 An innovative aspect of this drug delivery particle lies in the NP conjugation of a histone deacetylase (HDAC) inhibitor, CI-994 (Tacedinaline), introduced with a clickable acid-responsive prodrug during monomer synthesis, prior to polymerization. tacedinaline 130-142 histone deacetylase 9 Homo sapiens 84-103 25827403-2 2015 An innovative aspect of this drug delivery particle lies in the NP conjugation of a histone deacetylase (HDAC) inhibitor, CI-994 (Tacedinaline), introduced with a clickable acid-responsive prodrug during monomer synthesis, prior to polymerization. tacedinaline 130-142 histone deacetylase 9 Homo sapiens 105-109 18424067-6 2008 HDAC inhibitors, under clinical evaluation in the treatment of NSCLC patients, are pivanex, CI-994, vorinostat, and LBH589. tacedinaline 92-98 histone deacetylase 9 Homo sapiens 0-4