PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34482039-0	2021	Morphine treatment is associated with diminished telomere length together with down-regulated TERT and TERF2 mRNA levels.	Morphine	0-8	telomerase reverse transcriptase	Homo sapiens	94-98	
34482039-4	2021	To investigate whether telomere length is affected by morphine or not, the expressions of hTERT and TERF2 in morphine treated human SH-SY5Y cells were determined and compared with untreated cells.	Morphine	54-62	telomerase reverse transcriptase	Homo sapiens	90-95	
34482039-4	2021	To investigate whether telomere length is affected by morphine or not, the expressions of hTERT and TERF2 in morphine treated human SH-SY5Y cells were determined and compared with untreated cells.	Morphine	109-117	telomerase reverse transcriptase	Homo sapiens	90-95	
34482039-8	2021	RESULTS: The hTERT and TERF2 mRNA levels were down regulated in morphine treated cells as a function of exposure duration.	Morphine	64-72	telomerase reverse transcriptase	Homo sapiens	13-18	
34482039-11	2021	In the SH-SY5Y cells treated by 5 muM morphine for 60 consecutive days, the hTERT and TERF2 mRNA levels and relative telomere lengths remarkably decreased.	Morphine	38-46	telomerase reverse transcriptase	Homo sapiens	76-81	
34482039-12	2021	CONCLUSIONS: Reversible alteration of mRNA levels by removing morphine from culture medium, and effect of NAC in co-treatment of morphine plus NAC, emphasize the role of reactive oxygen species in down-regulation of the expression of hTERT and TERF2 by morphine.	Morphine	62-70	telomerase reverse transcriptase	Homo sapiens	234-239	
34482039-12	2021	CONCLUSIONS: Reversible alteration of mRNA levels by removing morphine from culture medium, and effect of NAC in co-treatment of morphine plus NAC, emphasize the role of reactive oxygen species in down-regulation of the expression of hTERT and TERF2 by morphine.	Morphine	129-137	telomerase reverse transcriptase	Homo sapiens	234-239	
34482039-12	2021	CONCLUSIONS: Reversible alteration of mRNA levels by removing morphine from culture medium, and effect of NAC in co-treatment of morphine plus NAC, emphasize the role of reactive oxygen species in down-regulation of the expression of hTERT and TERF2 by morphine.	Morphine	253-261	telomerase reverse transcriptase	Homo sapiens	234-239	
34482039-13	2021	Telomere attrition in morphine treated cells is a consequence of down-regulation of the expression of hTERT and TERF2.	Morphine	22-30	telomerase reverse transcriptase	Homo sapiens	102-107	
35298792-10	2022	It also elevated the telomerase activity and restored the expressions of human telomerase reverse transcriptase (hTERT) and TERF2 in morphine-induced M17 neuronal cells.	Morphine	133-141	telomerase reverse transcriptase	Homo sapiens	113-118