PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24107942-2 2013 Here, we establish an essential role for SIRT1 and SIRT2 in regulating behavioral responses to cocaine and morphine through actions in the nucleus accumbens (NAc), a key brain reward region. Morphine 107-115 sirtuin 2 Mus musculus 51-56 24107942-5 2013 Viral-mediated overexpression of SIRT1 or SIRT2 in the NAc enhances the rewarding effects of both cocaine and morphine. Morphine 110-118 sirtuin 2 Mus musculus 42-47