PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25318994-7	2015	Among them, bupropion and nifedipine showed high selectivity to CYP2C76.	Nifedipine	26-36	cytochrome P450 family 2 subfamily C member 76	Macaca fascicularis	64-71	
25318994-8	2015	As for nifedipine, CYP2C76 formed methylhydroxylated nifedipine, which was not produced by monkey CYP2C9, CYP2C19, or CYP3A4, as identified by mass spectrometry and estimated by a molecular docking simulation.	Nifedipine	7-17	cytochrome P450 family 2 subfamily C member 76	Macaca fascicularis	19-26	
25318994-8	2015	As for nifedipine, CYP2C76 formed methylhydroxylated nifedipine, which was not produced by monkey CYP2C9, CYP2C19, or CYP3A4, as identified by mass spectrometry and estimated by a molecular docking simulation.	Nifedipine	53-63	cytochrome P450 family 2 subfamily C member 76	Macaca fascicularis	19-26	
25318994-9	2015	This unique oxidative metabolite formation of nifedipine could be one of the selective marker reactions of CYP2C76 among the major CYP2Cs and CYP3As tested.	Nifedipine	46-56	cytochrome P450 family 2 subfamily C member 76	Macaca fascicularis	107-114	
25318994-10	2015	These results suggest that monkey CYP2C76 contributes to bupropion hydroxylation and formation of different nifedipine oxidative metabolites as a result of its relatively large substrate cavity.	Nifedipine	108-118	cytochrome P450 family 2 subfamily C member 76	Macaca fascicularis	34-41