PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17572501-7 2007 Our findings showed that MDMA produced neuronal apoptosis, accompanied by activation of caspase 3, in a concentration dependent manner. N-Methyl-3,4-methylenedioxyamphetamine 25-29 caspase 3 Homo sapiens 88-97 23194825-5 2013 MDMA catechol metabolites were neurotoxic to SH-SY5Y neurons, leading to caspase 3-independent cell death in a concentration- and time-dependent manner. N-Methyl-3,4-methylenedioxyamphetamine 0-4 caspase 3 Homo sapiens 73-82 17105935-0 2006 MDMA induces caspase-3 activation in the limbic system but not in striatum. N-Methyl-3,4-methylenedioxyamphetamine 0-4 caspase 3 Homo sapiens 13-22 17105935-4 2006 Therefore, the aim of the present article was to investigate whether treatment with MDMA produces activation of the caspase-3 enzyme, which is part of an enzymatic pathway involved in cell death, within limbic areas (i.e., hippocampus, amygdala, and piriform cortex) and striatum. N-Methyl-3,4-methylenedioxyamphetamine 84-88 caspase 3 Homo sapiens 116-125