PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10854087-1 2000 With the aim of evaluating the effects on blood pressure, platelet function and insulin sensitivity of the dihydropiridines lacidipine and nifedipine GITS, a parallel double-blind study was carried out in a group of 20 patients with mild to moderate essential hypertension. lacidipine 124-134 insulin Homo sapiens 80-87 9868030-2 1997 The results showed: (1) there were decreased in SOD activity and increased Lpo content the patients group (P < 0.01); (2) after treated with Lacidipine, the SOD acitvity increased and Lpo content decreased (P < 0.01); (3) Lacidipine had obvious antihypertensive effect with no significant changes in heart rate; (4) Lacidipine had no significant effects on insulin, blood glucose and lipids. lacidipine 144-154 insulin Homo sapiens 363-370 9868030-0 1997 [Effects of lacidipine on serum oxygen free radicals and fasting levels of insulin in patients with essential hypertension]. lacidipine 12-22 insulin Homo sapiens 75-82 8448066-15 1993 Thus, in "insulin sensitive" volunteers, lacidipine reduces fasting serum TG concentrations but has no effect on insulin-stimulated uptake of glucose, potassium and TG under euglycaemic hyperinsulinaemic conditions. lacidipine 41-51 insulin Homo sapiens 10-17 8076913-0 1994 Effects of the calcium antagonist lacidipine on insulin sensitivity in essential hypertension. lacidipine 34-44 insulin Homo sapiens 48-55