PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7637869-0	1995	Chronic L-DOPA treatment differentially regulates gene expression of glutamate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine-lesioned rat.	Levodopa	8-14	glutamate-ammonia ligase	Rattus norvegicus	69-92	
17241287-9	2007	Levodopa reversed the lesion-induced increase in the expression of cytochrome oxidase mRNA in the subthalamic nucleus and glutamate decarboxylase mRNA in the pars reticulata of the substantia nigra.	Levodopa	0-8	glutamate-ammonia ligase	Rattus norvegicus	122-145	
14667439-0	2004	Normalization of glutamate decarboxylase gene expression in the entopeduncular nucleus of rats with a unilateral 6-hydroxydopamine lesion correlates with increased GABAergic input following intermittent but not continuous levodopa.	Levodopa	222-230	glutamate-ammonia ligase	Rattus norvegicus	17-40	
12827644-5	2003	Our results provide original evidence that continuous L-DOPA normalizes the 6-OHDA-lesion-induced increase in mRNA levels encoding for the 67 kDa isoform of glutamate decarboxylase in neurons of the globus pallidus and cytochrome oxidase subunit I mRNA levels in the subthalamic nucleus.	Levodopa	54-60	glutamate-ammonia ligase	Rattus norvegicus	157-180	
12827644-7	2003	In addition, intermittent L-DOPA induced an increase in the mRNA levels encoding for the 65 kDa isoform of glutamate decarboxylase in globus pallidus neurons ipsilateral to the lesion and a bilateral increase in c-fos mRNA expression in the subthalamic nucleus.	Levodopa	26-32	glutamate-ammonia ligase	Rattus norvegicus	107-130	
12373737-1	2002	This study examined the consequences of systemic treatment with either L-dopa or MK-801 on the levels of mRNAs encoding the 65 and 67 kDa isoforms of glutamate decarboxylase (GAD65 and GAD67) in the striatum and globus pallidus (GP) of rats rendered hemiparkinsonian by intranigral 6-hydroxydopamine injection.	Levodopa	71-77	glutamate-ammonia ligase	Rattus norvegicus	150-173	
7637869-3	1995	Treatment with L-DOPA (200 mg/kg/24 h) for eight weeks reduced but did not abolish the 6-hydroxydopamine lesion-induced elevation of preproenkephalin messenger RNA and slightly reduced the elevation of glutamate decarboxylase (M(r) 67,000) messenger RNA in denervated striatum relative to intact side and control groups.	Levodopa	15-21	glutamate-ammonia ligase	Rattus norvegicus	202-225	
7637869-5	1995	The effect of L-DOPA on the gene expression of preproenkephalin and glutamate decarboxylase (M(r) 67,000) differs from the increase in striatal enkephalin content and glutamate decarboxylase activity previously found following L-DOPA treatment.	Levodopa	14-20	glutamate-ammonia ligase	Rattus norvegicus	68-91	
7637869-5	1995	The effect of L-DOPA on the gene expression of preproenkephalin and glutamate decarboxylase (M(r) 67,000) differs from the increase in striatal enkephalin content and glutamate decarboxylase activity previously found following L-DOPA treatment.	Levodopa	227-233	glutamate-ammonia ligase	Rattus norvegicus	68-91