PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2016306-7 1991 The 1-lyso-2-acetyl-GPC formed in this reaction is then further degraded to glycerophosphocholine, choline, or phosphocholine. Choline 90-97 glycophorin C (Gerbich blood group) Homo sapiens 20-23 1901090-7 1991 GPC is synthesized from choline, and the amount retained apparently may be controlled by the activity of GPC diesterase, an enzyme that catabolizes GPC. Choline 24-31 glycophorin C (Gerbich blood group) Homo sapiens 0-3 1901090-7 1991 GPC is synthesized from choline, and the amount retained apparently may be controlled by the activity of GPC diesterase, an enzyme that catabolizes GPC. Choline 24-31 glycophorin C (Gerbich blood group) Homo sapiens 105-108 1901090-7 1991 GPC is synthesized from choline, and the amount retained apparently may be controlled by the activity of GPC diesterase, an enzyme that catabolizes GPC. Choline 24-31 glycophorin C (Gerbich blood group) Homo sapiens 105-108 2827914-2 1988 This is based on GPC hydrolysis by a phosphodiesterase (PDE), free choline being then determined by the choline oxidase method. Choline 67-74 glycophorin C (Gerbich blood group) Homo sapiens 17-20 35168606-11 2022 Decreased expressions of GPCPD1 and GDE1 in choline metabolism led to an increased GPC levels in the PTX-resistant EOCs, which was observed as an elevated total choline (tCho) on in vivo 1H-MRS. Choline 161-168 glycophorin C (Gerbich blood group) Homo sapiens 83-86 35168606-11 2022 Decreased expressions of GPCPD1 and GDE1 in choline metabolism led to an increased GPC levels in the PTX-resistant EOCs, which was observed as an elevated total choline (tCho) on in vivo 1H-MRS. Choline 44-51 glycophorin C (Gerbich blood group) Homo sapiens 83-86 3444378-2 1987 Metabolic studies in both Raji and L1210 leukemic cells on OM-GPC, 3H-labeled in the methyl groups of the choline moiety, showed a (diacyl)-phosphatidylcholine as the only labeled metabolite. Choline 106-113 glycophorin C (Gerbich blood group) Homo sapiens 62-65 3444378-4 1987 One of these compounds, hexadecylphosphocholine (He-PC), which was 3H-labeled in the methyl-choline groups, showed a formation of labeled (diacyl)-phosphatidylcholine similar to that found with OM-GPC. Choline 40-47 glycophorin C (Gerbich blood group) Homo sapiens 197-200 6434535-8 1984 In related studies, cells were labeled with 1-O-hexadecyl-2-arachidonoyl-GPC containing a [methyl-14C] choline moiety. Choline 103-110 glycophorin C (Gerbich blood group) Homo sapiens 73-76 33951550-1 2021 In proton magnetic resonance spectroscopy (1H MRS) studies, aberrant levels of choline-containing compounds that include glycerophosphocholine plus phosphocholine (GPC+PC), can signify alterations in the metabolism of cellular membrane phospholipids (MPLs) from a healthy baseline. Choline 79-86 glycophorin C (Gerbich blood group) Homo sapiens 164-167 29042830-7 2017 Serum free choline was found to be elevated in the two A-GPC groups as compared to placebo (132% and 59% respectively). Choline 11-18 glycophorin C (Gerbich blood group) Homo sapiens 57-60 23940096-5 2014 The concentrations of choline-containing phospholipid metabolites (PC, GPC, and free Cho) and lactate were significantly elevated in recurrent cancer relative to surrounding benign tissues. Choline 22-29 glycophorin C (Gerbich blood group) Homo sapiens 71-74 26511472-2 2015 Choline-containing phospholipids (CCPLs) include phosphatidylcholine (PC), sphingomyelin (SM), and choline alphoscerate (GPC). Choline 0-7 glycophorin C (Gerbich blood group) Homo sapiens 121-124 26511472-5 2015 This paper has reviewed chemical, biological and therapeutic features of CCPLs by analyzing: a) effects of exogenous CCPLs, b) influence of GPC treatment on brain cholinergic neurotransmission, and c) neuroprotective effects of GPC alone or in association with acetylcholinesterase inhibitors in animal models of brain vascular injury, d) synthesis of the choline analogs, containing a short alkyl chain instead of a methyl group. Choline 163-170 glycophorin C (Gerbich blood group) Homo sapiens 140-143