PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29547875-11 2018 The fate of the acridone molecule (compound 10) in the P-glycoprotein environment is analyzed through analyzing the conformational changes occurring during the molecular dynamics simulations. acridone 16-24 ATP binding cassette subfamily B member 1 Homo sapiens 55-69 30429967-1 2018 "Acridine" along with its functional analogue "Acridone" is the most privileged pharmacophore in medicinal chemistry with diverse applications ranging from DNA intercalators, endonuclease mimics, ratiometric selective ion sensors, and P-glycoprotein inhibitors in countering the multi-drug resistance, enzyme inhibitors, and reversals of neurodegenerative disorders. acridone 47-55 ATP binding cassette subfamily B member 1 Homo sapiens 235-249 9415704-1 1997 Novel compounds, composed of two acridone moieties connected by a propyl or butyl spacer, were synthesized and tested as potential modulators of P-glycoprotein (P-gp)-mediated multidrug resistance. acridone 33-41 ATP binding cassette subfamily B member 1 Homo sapiens 161-165 33791212-7 2021 Molecular Docking studies of acridone derivatives with P-glycoprotein (P-gp), multiple resistant protein (MRP), and O6-methylguanine-DNA methyltransferase (MGMT) revealed different binding affinities to the transporters contributing to drug resistance. acridone 29-37 ATP binding cassette subfamily B member 1 Homo sapiens 55-69 33791212-7 2021 Molecular Docking studies of acridone derivatives with P-glycoprotein (P-gp), multiple resistant protein (MRP), and O6-methylguanine-DNA methyltransferase (MGMT) revealed different binding affinities to the transporters contributing to drug resistance. acridone 29-37 ATP binding cassette subfamily B member 1 Homo sapiens 71-75