PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16079483-4 2005 Western blot analysis showed that xanthoangelol markedly reduced the level of precursor caspase-3 and increased the level of cleaved caspase-3, but Bax and Bcl-2 proteins were not affected. xanthoangelol 34-47 caspase 3 Homo sapiens 88-97 16079483-4 2005 Western blot analysis showed that xanthoangelol markedly reduced the level of precursor caspase-3 and increased the level of cleaved caspase-3, but Bax and Bcl-2 proteins were not affected. xanthoangelol 34-47 caspase 3 Homo sapiens 133-142 16079483-5 2005 These results suggest that xanthoangelol induces apoptotic cell death by activatation of caspase-3 in neuroblastoma and leukemia cells through a mechanism that does not involve Bax/Bcl-2 signal transduction. xanthoangelol 27-40 caspase 3 Homo sapiens 89-98