PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30272282-6	2018	Furthermore, Sch B enhanced the expression of key antioxidant enzymes, including catalase, heme oxygenase-1, glutathione peroxidase, and superoxide dismutase, and further engaged the nuclear factor-erythroid 2-related factor 2 (Nrf2) signaling pathway by modulating its phosphorylation through activating multiple upstream kinases, including protein kinase B, adenosine monophosphate-activated protein kinase and mitogen-activated protein kinases (MAPKs).	schizandrin B	13-18	heme oxygenase 1	Homo sapiens	91-107	
28577438-9	2017	In addition, SchB increased the expression of Nrf2 and HO-1 in a concentration-dependent manner.	schizandrin B	13-17	heme oxygenase 1	Homo sapiens	55-59	
28846887-5	2017	Also, it was demonstrated that nuclear factor erythroid 2-related factor 2 (Nrf2) activation was involved in modulating cellular oxidative stress, where SchB promoted Nrf2 translocation into the nucleus and downstream target gene expression of heme oxygenase-1 (HO-1), NAD(P)H:quinone oxidoreductase 1 (NQO1) and Glutamate-cysteine ligase modifier subunit (GCLM).	schizandrin B	153-157	heme oxygenase 1	Homo sapiens	244-260