PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31798701-0 2019 Schisandrin B attenuates pressure overload-induced cardiac remodeling in mice by inhibiting the MAPK signaling pathway. schizandrin B 0-13 mitogen-activated protein kinase 1 Mus musculus 96-100 31798701-9 2019 Additionally, the phosphorylation levels of the mitogen-activated protein kinase (MAPK) signaling pathway-associated proteins extracellular signal-regulated kinase 1/2, c-Jun N-terminal kinase 1/2 and P38 mitogen-activated protein kinase were significantly lower in the Sch B-treated group compared with the TAC group. schizandrin B 270-275 mitogen-activated protein kinase 1 Mus musculus 82-86 31798701-10 2019 Further in vitro investigation demonstrated that Sch B prevented the adverse effects of angiotensin II-induced hypertrophy and fibrosis by inhibiting the MAPK signaling pathway in H9c2 cells. schizandrin B 49-54 mitogen-activated protein kinase 1 Mus musculus 154-158 31798701-11 2019 In conclusion, Sch B may improve pathological myocardial remodeling and cardiac function induced by pressure overload, and its underlying mechanism may be associated with inhibition of the MAPK signaling pathway. schizandrin B 15-20 mitogen-activated protein kinase 1 Mus musculus 189-193 21250784-0 2011 Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in AML12 hepatocytes. schizandrin B 0-13 mitogen-activated protein kinase 1 Mus musculus 112-115 21250784-1 2011 Abstract This study examined the effects of (-)schisandrin B [(-)Sch B] on MAPK and Nrf2 activation and the subsequent induction of glutathione antioxidant response and cytoprotection against apoptosis in AML12 hepatocytes. schizandrin B 47-60 mitogen-activated protein kinase 1 Mus musculus 75-79 21155602-7 2011 The results indicate that Sch B triggers the Raf/MEK/ERK signaling pathway, presumably by downregulating RKIP, thereby protecting against carbon tetrachloride-induced cytotoxicity. schizandrin B 26-31 mitogen-activated protein kinase 1 Mus musculus 53-56