PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16621244-2 2007 In this study, we revealed that Sch B was also an effective inhibitor of multidrug resistance-associated protein 1 (MRP1). schizandrin B 32-37 ATP binding cassette subfamily C member 1 Homo sapiens 116-120 27832326-7 2016 Schisandrin B (Sch B), a specific inhibitor of MRP1, can further increase the TMZ sensitivity in HDAC2-knocked down GBM cells. schizandrin B 0-13 ATP binding cassette subfamily C member 1 Homo sapiens 47-51 27832326-7 2016 Schisandrin B (Sch B), a specific inhibitor of MRP1, can further increase the TMZ sensitivity in HDAC2-knocked down GBM cells. schizandrin B 15-20 ATP binding cassette subfamily C member 1 Homo sapiens 47-51 16621244-0 2007 Schisandrin B: a dual inhibitor of P-glycoprotein and multidrug resistance-associated protein 1. schizandrin B 0-13 ATP binding cassette subfamily C member 1 Homo sapiens 54-95 16621244-2 2007 In this study, we revealed that Sch B was also an effective inhibitor of multidrug resistance-associated protein 1 (MRP1). schizandrin B 32-37 ATP binding cassette subfamily C member 1 Homo sapiens 73-114 16621244-5 2007 At the equimolar concentration, Sch B demonstrated significantly stronger potency than probenecid, a MRP1 inhibitor. schizandrin B 32-37 ATP binding cassette subfamily C member 1 Homo sapiens 101-105 16621244-6 2007 This study, together with the previous findings, demonstrated that Sch B was a dual inhibitor of P-gp and MRP1, a type suggested to be preferable to the use of combination of two specific modulators to prevent drug-drug interaction and cumulative toxicities. schizandrin B 67-72 ATP binding cassette subfamily C member 1 Homo sapiens 106-110 17129588-3 2007 The activities of 5 dibenzocyclooctadiene lignans (schisandrin A, schisandrin B, schisantherin A, schisandrol A, and schisandrol B) to reverse MRP1-mediated drug resistance were tested using HL60/Adriamycin (ADR) and HL60/Multidrug resistance-associated protein (MRP), two human promyelocytic leukemia cell lines with overexpression of MRP1 but not P-gp. schizandrin B 66-79 ATP binding cassette subfamily C member 1 Homo sapiens 143-147 17129588-3 2007 The activities of 5 dibenzocyclooctadiene lignans (schisandrin A, schisandrin B, schisantherin A, schisandrol A, and schisandrol B) to reverse MRP1-mediated drug resistance were tested using HL60/Adriamycin (ADR) and HL60/Multidrug resistance-associated protein (MRP), two human promyelocytic leukemia cell lines with overexpression of MRP1 but not P-gp. schizandrin B 66-79 ATP binding cassette subfamily C member 1 Homo sapiens 217-261 17129588-3 2007 The activities of 5 dibenzocyclooctadiene lignans (schisandrin A, schisandrin B, schisantherin A, schisandrol A, and schisandrol B) to reverse MRP1-mediated drug resistance were tested using HL60/Adriamycin (ADR) and HL60/Multidrug resistance-associated protein (MRP), two human promyelocytic leukemia cell lines with overexpression of MRP1 but not P-gp. schizandrin B 66-79 ATP binding cassette subfamily C member 1 Homo sapiens 143-146 17129588-3 2007 The activities of 5 dibenzocyclooctadiene lignans (schisandrin A, schisandrin B, schisantherin A, schisandrol A, and schisandrol B) to reverse MRP1-mediated drug resistance were tested using HL60/Adriamycin (ADR) and HL60/Multidrug resistance-associated protein (MRP), two human promyelocytic leukemia cell lines with overexpression of MRP1 but not P-gp. schizandrin B 66-79 ATP binding cassette subfamily C member 1 Homo sapiens 336-340