PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20829061-6 2010 Furthermore, GW2580, a c-FMS kinase inhibitor, inhibited the induction of MCP-1 by M-CSF or IL-34 in a concentration dependent manner. 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine 13-19 colony stimulating factor 1 Homo sapiens 83-88 32973322-8 2020 We show that a specific CSF-1R kinase inhibitor, GW2580, abolishes CSF-1 induced trophoblast cell proliferation and migration and can be cytotoxic. 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine 49-55 colony stimulating factor 1 Homo sapiens 24-29 25886134-9 2015 Through in vitro studies, we show that M-CSF and IL-34 upregulate CD163, a marker for type 2 activation of MPhis (M2), by primary monocytes, which is attenuated by the addition of GW2580. 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine 180-186 colony stimulating factor 1 Homo sapiens 39-44 20008303-5 2010 Here, we use the selective pharmacologic inhibitor of CSF1R signaling, GW2580, to demonstrate that CSF-1 regulates the tumor recruitment of CD11b(+)Gr-1(lo)Ly6C(hi) mononuclear MDSCs. 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine 71-77 colony stimulating factor 1 Homo sapiens 99-104