PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35572519-10	2022	Regarding the direct effect of BHB on inflammasome activation, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha secretion in response to adenosine triphosphate or palmitate stimulation in human macrophages decreased significantly after isocaloric KD.	3-Hydroxybutyric Acid	31-34	interleukin 1 beta	Homo sapiens	63-80	
25686106-9	2015	BHB reduces NLRP3 inflammasome-mediated interleukin (IL)-1beta and IL-18 production in human monocytes.	3-Hydroxybutyric Acid	0-3	interleukin 1 beta	Homo sapiens	40-62	
30218403-4	2018	Our results indicated that administration of BHB suppressed C6 cells migration and NLRP3 inflammasome activation, reducing the levels of activated cysteinyl aspartate-specific proteinase 1 (caspase-1) and mature Interleukin 1beta (IL-1beta).	3-Hydroxybutyric Acid	45-48	interleukin 1 beta	Homo sapiens	212-229	
30218403-4	2018	Our results indicated that administration of BHB suppressed C6 cells migration and NLRP3 inflammasome activation, reducing the levels of activated cysteinyl aspartate-specific proteinase 1 (caspase-1) and mature Interleukin 1beta (IL-1beta).	3-Hydroxybutyric Acid	45-48	interleukin 1 beta	Homo sapiens	231-239	
30218403-6	2018	BHB also counteracted the LPS/ATP-promoted cell migration by suppressing the activation of caspase-1 and the maturation of IL-1beta.	3-Hydroxybutyric Acid	0-3	interleukin 1 beta	Homo sapiens	123-131