PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31429167-0	2019	Apatinib induces 3-hydroxybutyric acid production in the liver of mice by peroxisome proliferator-activated receptor alpha activation to aid its antitumor effect.	3-Hydroxybutyric Acid	17-38	peroxisome proliferator activated receptor alpha	Mus musculus	74-122	
24361452-3	2014	Ketogenesis is modulated by the activity of peroxisome proliferator-activated receptor alpha (PPARalpha), and treatment with a PPAR activator has been shown to induce a marked increase in plasma acetoacetate and decreased beta-hydroxybutyrate in mice, accompanied by increased slow-wave activity during non-rapid eye movement (NREM) sleep.	3-Hydroxybutyric Acid	222-242	peroxisome proliferator activated receptor alpha	Mus musculus	94-103	
27367842-5	2016	Certain PPARalpha target genes such as Fgf21 remain repressed in the fetal liver and become PPARalpha responsive after birth following an epigenetic switch triggered by beta-hydroxybutyrate-mediated inhibition of HDAC3.	3-Hydroxybutyric Acid	169-189	peroxisome proliferator activated receptor alpha	Mus musculus	8-17	
27367842-5	2016	Certain PPARalpha target genes such as Fgf21 remain repressed in the fetal liver and become PPARalpha responsive after birth following an epigenetic switch triggered by beta-hydroxybutyrate-mediated inhibition of HDAC3.	3-Hydroxybutyric Acid	169-189	peroxisome proliferator activated receptor alpha	Mus musculus	92-101	
30954274-10	2019	BHBA also promoted the phosphorylation of AMPK and upregulated PPARalpha in the epileptic hippocampus.	3-Hydroxybutyric Acid	0-4	peroxisome proliferator activated receptor alpha	Mus musculus	63-72	
30954274-11	2019	In conclusion, BHBA attenuates neuronal damage in epileptic mice, which is associated with its anti-apoptotic and anti-oxidative effects as well as the activation of AMPK and PPARalpha.	3-Hydroxybutyric Acid	15-19	peroxisome proliferator activated receptor alpha	Mus musculus	175-184