PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25774170-7 2012 Treatment of rats with gastrodin or Madopar at 28 days significantly reduced interleukin-1beta expression. gastrodin 23-32 interleukin 1 beta Rattus norvegicus 77-94 24020812-0 2013 Gastrodin ameliorates anxiety-like behaviors and inhibits IL-1beta level and p38 MAPK phosphorylation of hippocampus in the rat model of posttraumatic stress disorder. gastrodin 0-9 interleukin 1 beta Rattus norvegicus 58-66 24020812-6 2013 However, repeated treatment with gastrodin, particularly at higher doses, reversed the aforementioned changes, including anxiety-like behavior, levels of IL-6 and IL-1beta, and the expression of iNOS and the p38 MAPK phosphorylation. gastrodin 33-42 interleukin 1 beta Rattus norvegicus 163-171 25774170-10 2012 Gastrodin could protect dopaminergic neurons via inhibition of interleukin-1beta expression and neuroinflammation in the substantia nigra. gastrodin 0-9 interleukin 1 beta Rattus norvegicus 63-80 29101808-0 2018 Gastrodin reduces IL-1beta-induced apoptosis, inflammation, and matrix catabolism in osteoarthritis chondrocytes and attenuates rat cartilage degeneration in vivo. gastrodin 0-9 interleukin 1 beta Rattus norvegicus 18-26 29101808-5 2018 Our results showed that gastrodin could prevent chondrocyte apoptosis induced by IL-1beta. gastrodin 24-33 interleukin 1 beta Rattus norvegicus 81-89 29101808-6 2018 Additionally, gastrodin suppressed the nuclear factor kappa B (NF-kappaB) pathway, decreased the release of inflammatory mediators (IL-6, TNF-alpha), and reduced matrix catabolism in IL-1beta-treated chondrocytes. gastrodin 14-23 interleukin 1 beta Rattus norvegicus 183-191