PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29101808-6	2018	Additionally, gastrodin suppressed the nuclear factor kappa B (NF-kappaB) pathway, decreased the release of inflammatory mediators (IL-6, TNF-alpha), and reduced matrix catabolism in IL-1beta-treated chondrocytes.	gastrodin	14-23	tumor necrosis factor	Rattus norvegicus	138-147	
31026457-5	2019	Gastrodin inhibited the expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor-alpha (TNF-alpha), cyclin-D1 and Ki67 in lipopolysaccharide (LPS)-stimulated BV-2 or primary microglia.	gastrodin	0-9	tumor necrosis factor	Rattus norvegicus	78-105	
31026457-5	2019	Gastrodin inhibited the expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor-alpha (TNF-alpha), cyclin-D1 and Ki67 in lipopolysaccharide (LPS)-stimulated BV-2 or primary microglia.	gastrodin	0-9	tumor necrosis factor	Rattus norvegicus	107-116	
33095377-12	2021	In addition, combination of DAPT and Gastrodin cumulatively decreased tumor necrosis factor-alpha (TNF-alpha) expression.	gastrodin	37-46	tumor necrosis factor	Rattus norvegicus	70-97	
33095377-12	2021	In addition, combination of DAPT and Gastrodin cumulatively decreased tumor necrosis factor-alpha (TNF-alpha) expression.	gastrodin	37-46	tumor necrosis factor	Rattus norvegicus	99-108	
31026457-10	2019	Moreover, treatment with LiCl, a special Wnt/beta-catenin pathway agonist significantly blocked Gastrodin-mediated down-regulation of iNOS, TNF-alpha, cyclin-D1, NO and the number of cells in the G2/M+S phase of cell cycle in LPS-stimulated BV-2 microglia.	gastrodin	96-105	tumor necrosis factor	Rattus norvegicus	140-149	
30959452-3	2019	The results show that gastrodin decreased cell viability, tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) release, and inducible nitrix oxide synthase (iNOS) and glial fibrillary acidic protein (GFAP) expression in TCDD-treated C6 cells.	gastrodin	22-31	tumor necrosis factor	Rattus norvegicus	58-85	
30959452-3	2019	The results show that gastrodin decreased cell viability, tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) release, and inducible nitrix oxide synthase (iNOS) and glial fibrillary acidic protein (GFAP) expression in TCDD-treated C6 cells.	gastrodin	22-31	tumor necrosis factor	Rattus norvegicus	87-96	
35249878-7	2022	Treatment with gastrodin injection obviously alleviated lung inflammation, decreased the wet/dry weight ratio of the lungs (P < 0.05), and significantly lowered TNF-alpha level (P < 0.01) and increased IL-10 level in the arterial blood in the rat models (P < 0.01); gastrodin injection also significantly decreased the protein expressions of NF-kappaB p65 and TNF-alpha (P < 0.05) and up-regulated the expressions of NGF and TrkA in the lung tissue of the rats (P < 0.05).	gastrodin	15-24	tumor necrosis factor	Rattus norvegicus	161-170	
23376120-4	2013	Our results showed that gastrodin treatment strongly suppressed nuclear factor-kappaB (NF-kappaB) and mitogen-activated protein kinases (MAPKs) family activation and upregulation of the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) in LPS-stimulated H9c2 cardiomyocytes.	gastrodin	24-33	tumor necrosis factor	Rattus norvegicus	266-293	
23376120-4	2013	Our results showed that gastrodin treatment strongly suppressed nuclear factor-kappaB (NF-kappaB) and mitogen-activated protein kinases (MAPKs) family activation and upregulation of the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) in LPS-stimulated H9c2 cardiomyocytes.	gastrodin	24-33	tumor necrosis factor	Rattus norvegicus	295-304	
34541406-7	2022	Interestingly, the obvious anti-inflammatory response was observed in 5%Gastrodin/PU by reduced expression of TNF-alpha and iNOS, which also evidenced by the few fibrous capsule formation in the subcutaneous implantation.	gastrodin	72-81	tumor necrosis factor	Rattus norvegicus	110-119	
34109563-7	2022	Gastrodin mimicked the effects of DAPT by inhibiting the LPS-induced expression of IL-1beta, IL-6, IL-23, TNF-alpha and NO.	gastrodin	0-9	tumor necrosis factor	Rattus norvegicus	106-115	
35249878-7	2022	Treatment with gastrodin injection obviously alleviated lung inflammation, decreased the wet/dry weight ratio of the lungs (P < 0.05), and significantly lowered TNF-alpha level (P < 0.01) and increased IL-10 level in the arterial blood in the rat models (P < 0.01); gastrodin injection also significantly decreased the protein expressions of NF-kappaB p65 and TNF-alpha (P < 0.05) and up-regulated the expressions of NGF and TrkA in the lung tissue of the rats (P < 0.05).	gastrodin	15-24	tumor necrosis factor	Rattus norvegicus	360-369