PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23578476-0 2013 Gastrodin stimulates anticancer immune response and represses transplanted H22 hepatic ascitic tumor cell growth: Involvement of NF-kappaB signaling activation in CD4+ T cells. gastrodin 0-9 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 129-138 27909971-5 2017 Furthermore, gastrodin attenuated the PTZ-induced microglial activation along with inhibition of mitogen-activated protein kinases, cAMP response element binding protein, and NF-kappaB. gastrodin 13-22 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 175-184 23578476-9 2013 Gastrodin administration specifically upregulated mRNA levels of several nuclear factor kappaB (NF-kappaB) responsive genes in CD4+ T cells but not in CD8+ T cells. gastrodin 0-9 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 88-94 23578476-9 2013 Gastrodin administration specifically upregulated mRNA levels of several nuclear factor kappaB (NF-kappaB) responsive genes in CD4+ T cells but not in CD8+ T cells. gastrodin 0-9 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 96-105 23578476-10 2013 Chromatin immunoprecipitation assay showed that gastrodin increased the association of NF-kappaB p65 subunit to the promoter regions of IL-2 and Bcl-2 encoding genes in CD4+ T cells. gastrodin 48-57 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 90-96 32473572-6 2020 Furthermore, GTD treatment could significantly inhibit inflammation-related signaling pathways activated by LPS/GalN, including the suppression of nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) and nuclear factor-kappa B (NF-kappaB) activation. gastrodin 13-16 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 215-237 32473572-6 2020 Furthermore, GTD treatment could significantly inhibit inflammation-related signaling pathways activated by LPS/GalN, including the suppression of nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) and nuclear factor-kappa B (NF-kappaB) activation. gastrodin 13-16 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 239-248 32473572-8 2020 Taken together, our investigation indicated that GTD played an essential role in liver protection by relieving hepatocyte apoptosis and inflammation reaction, which may be closely involved in the inhibition of NLRP3 inflammasome and NF-kappaB activation, regulation of apoptosis-related proteins expression, and the recovery of AMPK/ACC/autophagy. gastrodin 49-52 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 233-242 30959452-6 2019 Gastrodin inhibited TCDD-induced NF-kappaB signalling activation by lessening the SSeCKS-TRAF6 interaction in vitro. gastrodin 0-9 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 33-42 30959452-7 2019 Gastrodin attenuated SSeCKS-TRAF6 interaction in vivo and protected mice from NF-kappaB signalling activation following TCDD exposure. gastrodin 0-9 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 78-87 30959452-9 2019 In summary, gastrodin inhibited TCDD-induced NF-kappaB signalling activation by lessening the SSeCKS-TRAF6 interaction, resulting in attenuated astrocyte activation and subsequent neuronal apoptosis. gastrodin 12-21 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 45-54