PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24932697-0 2014 Gastrodin protects against MPP(+)-induced oxidative stress by up regulates heme oxygenase-1 expression through p38 MAPK/Nrf2 pathway in human dopaminergic cells. gastrodin 0-9 NFE2 like bZIP transcription factor 2 Homo sapiens 120-124 24932697-11 2014 Taken together, these findings suggest that gastrodin can induce HO-1 expression through activation of p38 MAPK/Nrf2 signaling pathway, thereby protecting the SH-SY5Y cells from MPP(+)-induced oxidative cell death. gastrodin 44-53 NFE2 like bZIP transcription factor 2 Homo sapiens 112-116 33320446-8 2021 In addition, treatment with gastrodin increased Nrf2 nuclear translocation, thus enhancing the expression of downstream enzymes. gastrodin 28-37 NFE2 like bZIP transcription factor 2 Homo sapiens 48-52 29115830-0 2018 Gastrodin and Isorhynchophylline Synergistically Inhibit MPP+-Induced Oxidative Stress in SH-SY5Y Cells by Targeting ERK1/2 and GSK-3beta Pathways: Involvement of Nrf2 Nuclear Translocation. gastrodin 0-9 NFE2 like bZIP transcription factor 2 Homo sapiens 163-167 31749701-9 2019 Mechanistically, we found that GAS protects HUVECs from TBHP-induced cellular apoptosis by activating the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)/heme oxygenase 1 (HO-1) pathway. gastrodin 31-34 NFE2 like bZIP transcription factor 2 Homo sapiens 151-155 31134531-0 2019 Nrf2 Mediates the Anti-apoptotic and Anti-inflammatory Effects Induced by Gastrodin in Hydrogen Peroxide-Treated SH-SY5Y Cells. gastrodin 74-83 NFE2 like bZIP transcription factor 2 Homo sapiens 0-4 29115830-3 2018 Thus, the studies reported were designed to test the hypothesis that gastrodin (GAS)-induced de novo synthesis of nuclear factor E2-related factor 2 (Nrf2) and isorhynchophylline (IRN) inhibition of Nrf2 nuclear export contribute to their additive or synergistic neuroprotective effect. gastrodin 69-78 NFE2 like bZIP transcription factor 2 Homo sapiens 150-154 29115830-3 2018 Thus, the studies reported were designed to test the hypothesis that gastrodin (GAS)-induced de novo synthesis of nuclear factor E2-related factor 2 (Nrf2) and isorhynchophylline (IRN) inhibition of Nrf2 nuclear export contribute to their additive or synergistic neuroprotective effect. gastrodin 69-78 NFE2 like bZIP transcription factor 2 Homo sapiens 199-203