PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35609324-13	2022	In conclusion, the present study suggested that gastrodin has a protective effect on OGD/R-induced R28 cell injury, which is achieved through the activation of the PI3K/AKT/Nrf2 signaling pathway.	gastrodin	48-57	NFE2 like bZIP transcription factor 2	Rattus norvegicus	173-177	
32115506-9	2020	Moreover, gastrodin increased the protein expression of nuclear factor erythroid 2-related factor 2 (Nrf2), GPX4, ferroportin-1 (FPN1), and heme oxygenase-1 (HO-1) in C6 cells treated with H2O2.	gastrodin	10-19	NFE2 like bZIP transcription factor 2	Rattus norvegicus	56-99	
32115506-9	2020	Moreover, gastrodin increased the protein expression of nuclear factor erythroid 2-related factor 2 (Nrf2), GPX4, ferroportin-1 (FPN1), and heme oxygenase-1 (HO-1) in C6 cells treated with H2O2.	gastrodin	10-19	NFE2 like bZIP transcription factor 2	Rattus norvegicus	101-105	
29545917-0	2018	Gastrodin alleviates glucocorticoid induced osteoporosis in rats via activating the Nrf2 signaling pathways.	gastrodin	0-9	NFE2 like bZIP transcription factor 2	Rattus norvegicus	84-88	
31727597-9	2020	Moreover, gastrodin administration significantly reduced levels of ROS, 8-OHDG, 3-Nitrotyrosine and MDA, while increased GSH-Px and SOD activity, and stimulated the upregulation of Keap1, Nrf2, and HO-1 signaling at 72 hours post-ICH.	gastrodin	10-19	NFE2 like bZIP transcription factor 2	Rattus norvegicus	188-192	
30673960-5	2019	Mechanistically, gastrodin significantly reduced the oxidative stress and inflammatory response, up-regulated the expression of nuclear factor erythroid 2-related factor 2, heme oxygenase-1, phospho-Akt and B-cell lymphoma 2, and down-regulated the expression of BCL2-associated X protein and cleaved caspase-3.	gastrodin	17-26	NFE2 like bZIP transcription factor 2	Rattus norvegicus	128-171	
29545917-9	2018	Furthermore, gastrodin protected osteoblasts by activating the nuclear factor erythroid derived 2-related factor-2 (Nrf2) pathway.	gastrodin	13-22	NFE2 like bZIP transcription factor 2	Rattus norvegicus	116-120	
29545917-11	2018	Conclusions: These findings suggest that gastrodin alleviated glucocorticoid-induced osteoporosis in rats by protecting osteoblasts via the Nrf2 regulated mitochondrial and ER stress-related signaling pathways.	gastrodin	41-50	NFE2 like bZIP transcription factor 2	Rattus norvegicus	140-144	
22982592-0	2012	Gastrodin protect primary cultured rat hippocampal neurons against amyloid-beta peptide-induced neurotoxicity via ERK1/2-Nrf2 pathway.	gastrodin	0-9	NFE2 like bZIP transcription factor 2	Rattus norvegicus	121-125	
26634892-0	2016	Gastrodin Ameliorates Oxidative Stress and Proinflammatory Response in Nonalcoholic Fatty Liver Disease through the AMPK/Nrf2 Pathway.	gastrodin	0-9	NFE2 like bZIP transcription factor 2	Rattus norvegicus	121-125	
22982592-4	2012	Pre-treatment of primary hippocampal neurons with gastrodin significantly attenuated Abeta(1-42)-induced neurotoxicity and changes in SOD and CAT, and upregulated gene expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and extracellular signal-regulated kinases 1 and 2 (ERK1/2) phosphorylation.	gastrodin	50-59	NFE2 like bZIP transcription factor 2	Rattus norvegicus	182-225	
22982592-4	2012	Pre-treatment of primary hippocampal neurons with gastrodin significantly attenuated Abeta(1-42)-induced neurotoxicity and changes in SOD and CAT, and upregulated gene expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and extracellular signal-regulated kinases 1 and 2 (ERK1/2) phosphorylation.	gastrodin	50-59	NFE2 like bZIP transcription factor 2	Rattus norvegicus	227-231